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Mouse Anti-DIP2A Antibody (1B10) (CBMAB-0029-YC)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
1B10
Antibody Isotype
IgG2a
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DIP2 disco-interacting protein 2 homolog A (Drosophila)
Introduction
Disco-interacting protein 2 homolog A (DIP2A) is a protein that in humans is encoded by the DIP2A gene. This gene is not highly expressed. Several transcript variants encoding different isoforms have been found for this gene. The protein may be involved in axon patterning in the central nervous system.
Entrez Gene ID
UniProt ID
Alternative Names
DIP2; C21orf106
Function
Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity).

Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity).

Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (PubMed:20054002).
Biological Process
Acetyl-CoA biosynthetic process Source: UniProtKB
Dendritic spine morphogenesis Source: UniProtKB
Negative regulation of gene expression Source: UniProtKB
Positive regulation of peptidyl-lysine acetylation Source: UniProtKB
Cellular Location
Cell membrane; Mitochondrion; Dendritic spine
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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