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Rabbit Anti-CSTF1 Recombinant Antibody (EG853) (CBMAB-EN1020-LY)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG853
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from N-terminal of human CSTF1.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cleavage Stimulation Factor Subunit 1
Introduction
CSTF1 (Cleavage Stimulation Factor Subunit 1) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and RNA Polymerase II Transcription Termination. Gene Ontology (GO) annotations related to this gene include RNA binding.
Entrez Gene ID
Human1477
Mouse67337
Rat311670
UniProt ID
HumanQ05048
MouseQ99LC2
RatQ5BJQ6
Alternative Names
Cleavage Stimulation Factor Subunit 1; Cleavage Stimulation Factor, 3 Pre-RNA, Subunit 1, 50kD; Cleavage Stimulation Factor 50 KDa Subunit; CF-1 50 KDa Subunit; CSTF 50 KDa Subunit; CstF-50; Cleavage Stimulation Factor, 3 Pre-RNA, Subunit 1, 50kDa; Cleavage Stimulation Factor, 3 Pre-RNA, Subunit 1; CstFp50;
Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (PubMed:10669729).

May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (PubMed:10669729).
Biological Process
mRNA 3'-end processing Source: Reactome
mRNA splicing, via spliceosome Source: Reactome
Termination of RNA polymerase II transcription Source: Reactome
Cellular Location
Nucleus
PTM
The N-terminus is blocked.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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