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Mouse Anti-CSTF1 Recombinant Antibody (CBFYC-2364) (CBMAB-C2436-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-2364
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
CSTF1 (NP_001315.1, 332 a.a.-431 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cleavage Stimulation Factor Subunit 1
Introduction
CSTF1 (Cleavage Stimulation Factor Subunit 1) is a Protein Coding gene. Among its related pathways are mRNA Splicing-Major Pathway and RNA Polymerase II Transcription Termination. Gene Ontology (GO) annotations related to this gene include RNA binding.
Entrez Gene ID
1477
UniProt ID
Q05048
Alternative Names
Cleavage Stimulation Factor Subunit 1; Cleavage Stimulation Factor, 3 Pre-RNA, Subunit 1, 50kD; Cleavage Stimulation Factor 50 KDa Subunit; CF-1 50 KDa Subunit; CSTF 50 KDa Subunit; CstF-50; Cleavage Stimulation Factor, 3 Pre-RNA, Subunit 1, 50kDa; Cleavage Stimulation Factor, 3 Pre-RNA, Subunit 1; CstFp50
Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (PubMed:10669729).

May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (PubMed:10669729).
Biological Process
mRNA 3'-end processing Source: Reactome
mRNA splicing, via spliceosome Source: Reactome
Termination of RNA polymerase II transcription Source: Reactome
Cellular Location
Nucleus
PTM
The N-terminus is blocked.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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