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Mouse Anti-CSNK1G1 (AA 163-422) Recombinant Antibody (CBFYC-2299) (CBMAB-C2371-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-2299
Antibody Isotype
IgG1
Application
IHC-P

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 163-422 of human CSNK1G1(NP_071331) produced in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 163-422

Target

Full Name
Casein Kinase 1 Gamma 1
Introduction
CSNK1G1 (Casein Kinase 1 Gamma 1) is a Protein Coding gene. Diseases associated with CSNK1G1 include Epileptic Encephalopathy, Early Infantile, 15. Among its related pathways are FoxO family signaling and Regulation of lipid metabolism Insulin signaling-generic cascades. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CSNK1G3.
Entrez Gene ID
53944
UniProt ID
Q9HCP0
Alternative Names
Casein Kinase 1 Gamma 1; EC 2.7.11.1; Casein Kinase I Isoform Gamma-1; Casein Kinase 1, Gamma 1; CKI-Gamma 1; CK1gamma1; EC 2.7.1
Function
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).

Phosphorylates CLSPN.
Biological Process
Endocytosis Source: GO_Central
Peptidyl-serine phosphorylation Source: ParkinsonsUK-UCL
Positive regulation of canonical Wnt signaling pathway Source: GO_Central
Wnt signaling pathway Source: GO_Central
Cellular Location
Cytoplasm
PTM
Autophosphorylated.
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For research use only. Not intended for any clinical use.

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