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Rabbit Anti-COIL Recombinant Antibody (CBWJC-2902) (CBMAB-C4029WJ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBWJC-2902
Antibody Isotype
IgG
Application
WB, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Coilin
Introduction
COIL (Coilin) is a Protein Coding gene. Diseases associated with COIL include Spinal Muscular Atrophy and Ischemic Neuropathy. Among its related pathways are Translational Control. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein C-terminus binding.
Entrez Gene ID
8161
UniProt ID
P38432
Alternative Names
Coilin; P80-Coilin; CLN80; Coilin P80; P80;
Function
Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Biological Process
Spliceosomal snRNP assembly Source: GO_Central
Cellular Location
Nucleus; Cajal body
PTM
Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs.
Phosphorylation during mitosis is associated with disassembly of CBs.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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