Rat Anti-CNTN3 Recombinant Antibody (RM0404-5V11) (CBMAB-1408-CN)

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Summary

Host Animal

Rat

Specificity

Mouse

Clone

RM0404-5V11

Antibody Isotype

IgG2

Application

Basic Information

Immunogen

Recombinant full length protein corresponding to Mouse Contactin 3 aa. 20-1003. Full length chain without signal or propetide.

Specificity

Mouse

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Contactin 3

Introduction

Contactins mediate cell surface interactions during nervous system development. It has some neurite outgrowth-promoting activity.

Entrez Gene ID

18488

UniProt ID

Q07409

Alternative Names

Pang

Function

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity).

Biological Process

Cell adhesion Source: UniProtKB-KW
Nervous system development Source: Ensembl

Cellular Location

Cell membrane

More Infomation

References

Korotkov, A., Luinenburg, M. J., Romagnolo, A., Zimmer, T. S., van Scheppingen, J., Bongaarts, A., ... & Aronica, E. (2022). Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period. Journal of neurodevelopmental disorders, 14(1), 1-16.

Mamoor, S. (2021). CNTN3 is differentially expressed in lymph node metastasis in human breast cancer.

Zhou, J., Xie, Z., Cui, P., Su, Q., Zhang, Y., Luo, L., ... & Huang, J. (2020). SLC1A1, SLC16A9, and CNTN3 are potential biomarkers for the occurrence of colorectal cancer. BioMed Research International, 2020.

Zhu, Y. F., Guo, Y. B., Zhang, H. Y., Yang, P., Wei, D. F., Zhang, T. T., ... & Liu, L. (2019). Prognostic significance of contactin 3 expression and associated genes in glioblastoma multiforme. Oncology Letters, 18(2), 1863-1871.

Peng, X., Williams, J., Smallwood, P. M., & Nathans, J. (2019). Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis. Plos one, 14(7), e0219384.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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