Rat Anti-CNTN3 Recombinant Antibody (CBFYC-2017) (CBMAB-C2083-FY)

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Datasheet

Summary

Host Animal

Rat

Specificity

Mouse

Clone

CBFYC-2017

Application

FC, WB

Basic Information

Immunogen

Recombinant protein corresponding to mouse Contactin-3

Specificity

Mouse

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Contactin 3

Introduction

CNTN3 (Contactin 3) is a Protein Coding gene. Diseases associated with CNTN3 include Parotid Proline-Rich Salivary Protein Pc and Plasmacytoma. Among its related pathways are Metabolism of proteins and Post-translational modification-synthesis of GPI-anchored proteins. An important paralog of this gene is CNTN4.

Entrez Gene ID

18488

UniProt ID

Q07409

Alternative Names

Pang; contactin-3; BIG-1; brain-derived immunoglobulin superfamily protein 1; plasmacytoma-associated neuronal glycoprotein

Function

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity).

Biological Process

Cell adhesion Source: UniProtKB-KW
Nervous system development Source: Ensembl

Cellular Location

Cell membrane

More Infomation

References

Korotkov, A., Luinenburg, M. J., Romagnolo, A., Zimmer, T. S., van Scheppingen, J., Bongaarts, A., ... & Aronica, E. (2022). Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period. Journal of neurodevelopmental disorders, 14(1), 1-16.

Mamoor, S. (2021). CNTN3 is differentially expressed in lymph node metastasis in human breast cancer.

Zhou, J., Xie, Z., Cui, P., Su, Q., Zhang, Y., Luo, L., ... & Huang, J. (2020). SLC1A1, SLC16A9, and CNTN3 are potential biomarkers for the occurrence of colorectal cancer. BioMed Research International, 2020.

Zhu, Y. F., Guo, Y. B., Zhang, H. Y., Yang, P., Wei, D. F., Zhang, T. T., ... & Liu, L. (2019). Prognostic significance of contactin 3 expression and associated genes in glioblastoma multiforme. Oncology Letters, 18(2), 1863-1871.

Peng, X., Williams, J., Smallwood, P. M., & Nathans, J. (2019). Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis. Plos one, 14(7), e0219384.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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Second antibody and isotype control

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