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Mouse Anti-CNGA2 Recombinant Antibody (7B11) (CBMAB-0289-CN)


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Summary

Host Animal
Mouse
Specificity
Rat
Clone
7B11
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Specificity
Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cyclic Nucleotide Gated Channel Alpha 2
Introduction
Cyclic nucleotide gated channel alpha 2, also known as CNGA2, is a human gene encoding an ion channel protein. Cyclic nucleotide-gated ion channel is involved in signal transduction; may participate in neural communication and plasticity. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger.
Entrez Gene ID
25411
UniProt ID
Q00195
Alternative Names
Cncg4; OLFCH
Function
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Biological Process
Cilium assembly Source: Reactome
Response to stimulus Source: UniProtKB-KW
Sensory perception of smell Source: UniProtKB-KW
Cellular Location
Membrane
Topology
Cytoplasmic: 1-138
Helical: 139-159
Extracellular: 160-171
Helical: 172-192
Cytoplasmic: 193-224
Helical: 225-245
Extracellular: 246-274
Helical: 275-295
Cytoplasmic: 296-350
Helical: 351-371
Extracellular: 372-453
Helical: 454-474
Cytoplasmic: 475-662
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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