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Rabbit Anti-CARTPT Recombinant Antibody (D6M2M) (CBMAB-CP0094-LY)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
D6M2M
Antibody Isotype
IgG
Application
WB, IHC-P

Basic Information

Immunogen
Recombinant protein corresponding to the full-length human CART protein.
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000
IHC-P1:75

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, pH 7.5, 100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CART Prepropeptide
Entrez Gene ID
Human9607
Mouse27220
Rat29131
UniProt ID
HumanQ16568
MouseP56388
RatP49192
Function
Satiety factor closely associated with the actions of leptin and neuropeptide Y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro.
Biological Process
Activation of MAPKK activity Source: HGNC-UCL
Adult feeding behavior Source: HGNC-UCL
Cell-cell signaling Source: ProtInc
Cellular glucose homeostasis Source: HGNC-UCL
Cellular response to starvation Source: HGNC-UCL
Chemical synaptic transmission Source: UniProtKB-KW
Circadian regulation of gene expression Source: HGNC-UCL
G protein-coupled receptor signaling pathway Source: HGNC-UCL
Negative regulation of appetite Source: HGNC-UCL
Negative regulation of bone resorption Source: HGNC-UCL
Negative regulation of glucagon secretion Source: Ensembl
Negative regulation of osteoclast differentiation Source: HGNC-UCL
Neuropeptide signaling pathway Source: UniProtKB-KW
Positive regulation of blood pressure Source: HGNC-UCL
Positive regulation of epinephrine secretion Source: HGNC-UCL
Positive regulation of transmission of nerve impulse Source: HGNC-UCL
Regulation of insulin secretion Source: Ensembl
Signal transduction Source: ProtInc
Somatostatin secretion Source: Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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