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Rabbit Anti-CADM4 Recombinant Antibody (EG460) (CBMAB-EN520-LY)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG460
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Synthetic peptide corresponding to residues surrounding Ala372 of mouse CADM4/IgSF4C protein.
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, pH 7.5, 100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cell Adhesion Molecule 4
Introduction
CADM4 (Cell Adhesion Molecule 4) is a Protein Coding gene. Diseases associated with CADM4 include Renal Clear Cell Carcinoma and Cleft Lip/Palate-Ectodermal Dysplasia Syndrome. An important paralog of this gene is CADM1.
Entrez Gene ID
Human199731
Mouse260299
Rat365216
UniProt ID
HumanQ8NFZ8
MouseQ8R464
RatQ1WIM1
Alternative Names
Cell Adhesion Molecule 4; Immunoglobulin Superfamily Member 4C; Nectin-Like Protein 4; TSLC1-Like Protein 2; Nectin-Like 4; Necl-4; IGSF4C;
Function
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
Biological Process
Cell adhesion Source: UniProtKB-KW
Negative regulation of peptidyl-threonine phosphorylation Source: UniProtKB
Negative regulation of peptidyl-tyrosine phosphorylation Source: UniProtKB
Negative regulation of protein phosphorylation Source: UniProtKB
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: UniProtKB
Negative regulation of vascular endothelial growth factor signaling pathway Source: UniProtKB
Regulation of cell motility Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Regulation of protein phosphorylation Source: UniProtKB
Regulation of Rac protein signal transduction Source: UniProtKB
Regulation of wound healing Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 21-324 aa
Helical: 325-345 aa
Cytoplasmic: 346-388 aa
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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