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Rat Anti-CADM4 Recombinant Antibody (404619) (CBMAB-C6440-LY)


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Summary

Host Animal
Rat
Specificity
Human
Clone
404619
Antibody Isotype
IgG1
Application
FC, IC, IF, WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human IGSF4C/SynCAM4 Gln25-Tyr323.
Host Species
Rat
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1 µg/ml
IF(ICC)8-25 µg/ml
FC2.5 µg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, 5% trehalose
Preservative
None
Concentration
0.5 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cell Adhesion Molecule 4
Entrez Gene ID
199731
UniProt ID
Q8NFZ8
Function
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
Biological Process
Cell adhesion Source: UniProtKB-KW
Negative regulation of peptidyl-threonine phosphorylation Source: UniProtKB
Negative regulation of peptidyl-tyrosine phosphorylation Source: UniProtKB
Negative regulation of protein phosphorylation Source: UniProtKB
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: UniProtKB
Negative regulation of vascular endothelial growth factor signaling pathway Source: UniProtKB
Regulation of cell motility Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Regulation of protein phosphorylation Source: UniProtKB
Regulation of Rac protein signal transduction Source: UniProtKB
Regulation of wound healing Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 21-324 aa
Helical: 325-345 aa
Cytoplasmic: 346-388 aa
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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