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Mouse Anti-B3GNT2 Recombinant Antibody (1A8) (CBMAB-A0686-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1A8
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
B3GNT2 (NP_006568, 111 a.a. ~ 210 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Introduction
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. [provided by RefSeq]
Entrez Gene ID
10678
UniProt ID
Q9NY97
Alternative Names
B3GN-T1; B3GN-T2; B3GNT; B3GNT-2; B3GNT1; BETA3GNT
Function
Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646).
Probably constitutes the main polylactosamine synthase.
Biological Process
Axon guidance Source: Ensembl
Cellular response to leukemia inhibitory factor Source: Ensembl
Keratan sulfate biosynthetic process Source: Reactome
O-glycan processing Source: Reactome
Poly-N-acetyllactosamine biosynthetic process Source: UniProtKB
Protein glycosylation Source: GO_Central
Sensory perception of smell Source: Ensembl
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-7 aa
Helical: 8-28 aa
Lumenal: 29-397 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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