Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-ARID3A Recombinant Antibody (1A11) (CBMAB-A0475-LY)


See all ARID3A antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A11
Antibody Isotype
IgG1, κ
Application
WB, ELISA, IF, IHC

Basic Information

Immunogen
ARID3A (NP_005215, 317 a.a. ~ 416 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IF(ICC)10 µg/ml
IHC3 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ARID3A
Introduction
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq]
Entrez Gene ID
1820
UniProt ID
Q99856
Alternative Names
BRIGHT; DRIL1; DRIL3; E2FBP1
Function
Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.
Biological Process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Source: Reactome
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. Shuttles between nucleus and cytoplasm.
More Infomation

Tang, J., Yang, L., Li, Y., Ning, X., Chaulagain, A., Wang, T., & Wang, D. (2021). ARID3A promotes the development of colorectal cancer by upregulating AURKA. Carcinogenesis, 42(4), 578-586.

Garton, J. W., Shankar, M., Guthridge, J., James, J. A., & Webb, C. (2021). ARID3a Defines a Novel Subset of Naïve B Cells in SLE Patients.

Arman, K., Saadat, K. A., Igci, Y. Z., Bozgeyik, E., Ikeda, M. A., Cakmak, E. A., & Arslan, A. (2020). Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells. Cell Biology International, 44(11), 2263-2274.

Ratliff, M. L., Shankar, M., Guthridge, J. M., James, J. A., & Webb, C. F. (2020). TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNα production. Cellular immunology, 357, 104201.

Saadat, K. A., Bozgeyik, E., Arman, K., Bozgeyik, I., & Ikeda, M. A. (2020). ARID3A-mediated modulation of TP73 and TP73-AS1 in osteosarcoma cells. Gene Reports, 20, 100683.

Yoon, G., Park, J. Y., Kim, H. J., Choi, G. S., Kim, J. G., Kang, B. W., ... & Seo, A. N. (2019). ARID3A positivity correlated with favorable prognosis in patients with residual rectal cancer after Neoadjuvant chemoradiotherapy. Anticancer research, 39(6), 2845-2853.

Garton, J., Barron, M. D., Ratliff, M. L., & Webb, C. F. (2019). New Frontiers: ARID3a in SLE. Cells, 8(10), 1136.

Garton, J. W., Chapman, B., Shankar, M., Rose, K., & Webb, C. (2019). The DNA-binding protein ARID3a is Required for Human Erythrocyte Lineage Differentiation using the K562 Model Cell Line.

Garton, J. W., Pelikan, R., Ratliff, M., James, J. A., Gaffney, P., & Webb, C. F. (2018). Genes associated with ARID3a expression in B Lymphocytes from Systemic Lupus Erythematosus patients.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ARID3A Recombinant Antibody (1A11)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quoteOnline Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry