ZSCAN4

ZSCAN4 (Zinc Finger And SCAN Domain Containing 4) is a Protein Coding gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture. Diseases associated with ZSCAN4 include Facioscapulohumeral Muscular Dystrophy 1. Among its related pathways are Preimplantation Embryo.

zinc finger and SCAN domain containing 4

Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).

Biological Process negative regulation of mitotic recombination Source:BHF-UCLBy Similarity
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process telomere maintenance via telomere lengthening Source:UniProtKB

Nucleus
Chromosome, telomere