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Mouse Anti-ZSCAN4 Recombinant Antibody (3B1) (CBMAB-Z0772-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3B1
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to AA164-433 of human ZSCAN4 (NP_689890) produced in E. coli.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL

Target

Full Name
zinc finger and SCAN domain containing 4
Introduction
ZSCAN4 (Zinc Finger And SCAN Domain Containing 4) is a Protein Coding gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture. Diseases associated with ZSCAN4 include Facioscapulohumeral Muscular Dystrophy 1. Among its related pathways are Preimplantation Embryo.
Entrez Gene ID
201516
UniProt ID
Q8NAM6
Alternative Names
ZNF494
Function
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).
Biological Process
Biological Process negative regulation of mitotic recombination Source:BHF-UCLBy Similarity
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process telomere maintenance via telomere lengthening Source:UniProtKB
Cellular Location
Nucleus
Chromosome, telomere
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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