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ZBTB14

Transcriptional activator of the dopamine transporter (DAT), binding its promoter at the consensus sequence 5-CCTGCACAGTTCACGGA-3. Binds to 5-d(GCC)(n)-3 trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters.
Full Name
ZBTB14
Function
Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters.
Biological Process
Biological Process cardiac septum development Source:Ensembl
Biological Process coronary vasculature development Source:Ensembl
Biological Process heart valve development Source:Ensembl
Biological Process kidney development Source:Ensembl
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:ProtInc1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
Colocalizes with ZBTB21 in nucleus in HEK293 cells.

Anti-ZBTB14 antibodies

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Target: ZBTB14
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F7
Application*: WB, E
Target: ZBTB14
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F1
Application*: WB, E
Target: ZBTB14
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJZ-037
Application*: E, WB
Target: ZBTB14
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1B12
Application*: IP, E
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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