VSIG1

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

V-set and immunoglobulin domain containing 1

Biological Process epithelial cell morphogenesis Source:InterPro
Biological Process maintenance of gastrointestinal epithelium Source:GO_Central1 Publication

Membrane

Extracellular: 22-232
Helical: 233-253
Cytoplasmic: 254-387

Highly N-glycosylated. Appears not to contain significant amounts of O-linked carbohydrates or sialic acid in its sugar moieties.