VBP1

The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. [provided by RefSeq]

Full Name

von Hippel-Lindau binding protein 1

Function

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Biological Process

Biological Process microtubule-based process Source:GO_Central1 Publication
Biological Process negative regulation of amyloid fibril formation Source:FlyBase1 Publication
Biological Process protein folding Source:FlyBase1 Publication
Biological Process protein stabilization Source:ComplexPortal1 Publication
Biological Process tubulin complex assembly Source:GO_Central1 Publication

Cellular Location

Cytoplasm
Nucleus
In complex with VHL can translocate to the nucleus.

Anti-VBP1 antibodies

Mouse Anti-VBP1 Recombinant Antibody (3D11) (CBMAB-P3775-YC)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3D11

Application*: E, WB

Mouse Anti-VBP1 Recombinant Antibody (2G2) (CBMAB-P3774-YC)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Dog, Monkey

Clone: 2G2

Application*: WB, P

Mouse Anti-VBP1 Recombinant Antibody (1H5) (CBMAB-P3773-YC)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1H5

Application*: E, LA

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1320) (CBMAB-1354-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-1320

Application*: IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1319) (CBMAB-1353-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Dog, Rat, Monkey, Mouse

Clone: CBYY-1319

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1318) (CBMAB-1352-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-1318

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1317) (CBMAB-1350-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-1317

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1316) (CBMAB-1349-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Dog, Rat, Monkey, Mouse

Clone: CBYY-1316

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1315) (CBMAB-1348-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Dog, Rat, Monkey, Mouse

Clone: CBYY-1315

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1314) (CBMAB-1347-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-1314

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1313) (CBMAB-1346-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Dog, Rat, Monkey, Mouse

Clone: CBYY-1313

Application*: WB, IH

Mouse Anti-VBP1 Recombinant Antibody (CBYY-1312) (CBMAB-1343-YY)

Datasheet

SDS

Target: VBP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-1312

Application*: E, IH, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)