TRIM69

This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

TRIM69 Gene(Protein Coding)Tripartite Motif Containing 69

May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process protein ubiquitination Source:GO_Central1 Publication

Cytoplasm
Nucleus
Nucleus speckle

Phosphorylated. Phosphorylation is necessary for nuclear localization.