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Rabbit Anti-TRIM69 Recombinant Antibody (CBCNR-619) (CBMAB-R4079-CN)


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Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBCNR-619
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
TRIM69 Gene(Protein Coding)Tripartite Motif Containing 69
Introduction
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human140691
Mouse70928
Rat311373
UniProt ID
HumanQ86WT6
MouseQ80X56
RatQ5BK82
Alternative Names
Tripartite Motif Containing 69; RFP-Like Domain-Containing Protein Trimless; RING-Type E3 Ubiquitin Transferase TRIM69; Ring Finger Protein 36; RNF36; Tripartite Motif-Containing Protein 69; E3 Ubiquitin-Protein Ligase TRIM69;
Function
May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process protein ubiquitination Source:GO_Central1 Publication
Cellular Location
Cytoplasm
Nucleus
Nucleus speckle
PTM
Phosphorylated. Phosphorylation is necessary for nuclear localization.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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