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SYNPO

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).

Full Name

Synaptopodin

Function

Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).

Biological Process

Biological Process modification of dendritic spineIDA:SynGO1 Publication
Biological Process positive regulation of actin filament bundle assemblyISS:UniProtKB1 Publication
Biological Process regulation of stress fiber assemblyISS:UniProtKB
Biological Process spine apparatus assemblyIBA:GO_Central1 Publication

Cellular Location

Cytoplasm, cytoskeleton
Cell junction, tight junction
Perikaryon
Cell projection, dendritic spine
Postsynaptic density
Synapse
Cytoplasm, cytosol
Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.

PTM

O-glycosylated.

Anti-SYNPO antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-SYNPO Recombinant Antibody (G1D4) (CBMAB-S6338-CQ)

SDS

Target: SYNPO

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Pig, Rat, Gerbil, Guinea pig, Cattle

Clone: G1D4

Application*: WB, P, C

Mouse Anti-SYNPO Recombinant Antibody (CBXS-3549) (CBMAB-S6278-CQ)

SDS

Target: SYNPO

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Guinea pig, Human, Mouse, Rat

Clone: CBXS-3549

Application*: IF, IH, WB

Mouse Anti-SYNPO Recombinant Antibody (CBXS-3298) (CBMAB-S6037-CQ)

SDS

Target: SYNPO

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Guinea pig, Human, Mouse, Rat

Clone: CBXS-3298

Application*: IF, IH, WB

Mouse Anti-SYNPO Recombinant Antibody (CBXS-2500) (CBMAB-S5257-CQ)

SDS

Target: SYNPO

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Guinea pig, Mouse, Rat

Clone: CBXS-2500

Application*: IF

Mouse Anti-SYNPO Recombinant Antibody (CBXS-2499) (CBMAB-S5256-CQ)

SDS

Target: SYNPO

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Guinea pig, Mouse, Rat

Clone: CBXS-2499

Application*: IF, IH, WB

Mouse Anti-SYNPO Recombinant Antibody (CBXS-1979) (CBMAB-S4749-CQ)

SDS

Target: SYNPO

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-1979

Application*: IH

Mouse Anti-SYNPO Recombinant Antibody (CBXS-0910) (CBMAB-S3829-CQ)

SDS

Target: SYNPO

Host: Mouse

Specificity: Human

Clone: CBXS-0910

Application*: WB, IC, P, C, E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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