STX7

The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome.

Syntaxin 7

May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.

Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process organelle assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process organelle localizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of receptor localization to synapseManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of T cell mediated cytotoxicityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of protein localization to plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central

Early endosome membrane

Cytoplasmic: 2-238
Helical: 239-259
Vesicular: 260-261