SNRPB2

The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Full Name

small nuclear ribonucleoprotein polypeptide B''

Function

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed:9716128).

Biological Process

Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assembly1 PublicationIC:ComplexPortal

Cellular Location

Nucleus

Anti-SNRPB2 antibodies

Mouse Anti-SNRPB2 Recombinant Antibody (CBFYS-005) (CBMAB-S0005-FY)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBFYS-005

Application*: WB, IP, IF, E

Mouse Anti-SNRPB2 Recombinant Antibody (CBFYS-006) (CBMAB-S0006-FY)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYS-006

Application*: IF, IP, WB

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-5599) (CBMAB-S0477-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5599

Application*: P, WB

Mouse Anti-SNRPB2 Recombinant Antibody (2F4) (CBMAB-A8425-LY)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2F4

Application*: SE, E

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-3877) (CBMAB-S1146-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-3877

Application*: WB

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4082) (CBMAB-S1340-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4082

Application*: WB

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4353) (CBMAB-S1597-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4353

Application*: WB, IH

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4556) (CBMAB-S1796-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-4556

Application*: IC, IF, WB

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4586) (CBMAB-S1826-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4586

Application*: E

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4742) (CBMAB-S1971-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4742

Application*: IC, IF, WB

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4897) (CBMAB-S2119-CQ)

Datasheet

SDS

Target: SNRPB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4897

Application*: WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)