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PGD

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
Full Name
PGD
Function
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.
Biological Process
D-gluconate catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Pentose biosynthetic processIEA:Ensembl
Pentose-phosphate shuntISS:UniProtKB
Pentose-phosphate shunt, oxidative branchManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm

Anti-PGD antibodies

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Target: PGD
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYC-P322
Application*: IC, IF
Target: PGD
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 46B3
Application*: WB, E, IC, IF
Target: PGD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A5
Application*: WB, P, IF, IC
Target: PGD
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1G12
Application*: E, IF, IH, WB
Target: PGD
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 1B6
Application*: E, M
Target: PGD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-5053
Application*: E, IP
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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