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Mouse Anti-PGD Recombinant Antibody (46B3) (CBMAB-P1566-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
46B3
Antibody Isotype
IgG2b, κ
Application
WB, ELISA, ICC, IF

Basic Information

Immunogen
Recombinant human PGD (1-483aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PGD
Introduction
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
Entrez Gene ID
5226
UniProt ID
P52209
Alternative Names
Phosphogluconate Dehydrogenase; EC 1.1.1.44; 6-Phosphogluconate Dehydrogenase, Decarboxylating; PGDH; PGD;
Function
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.
Biological Process
D-gluconate catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Pentose biosynthetic processIEA:Ensembl
Pentose-phosphate shuntISS:UniProtKB
Pentose-phosphate shunt, oxidative branchManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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