PCDH1

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq]

protocadherin 1

May be involved in cell-cell interaction processes and in cell adhesion.

Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc

Cell junction
Cell membrane
Found at cell-cell boundaries and probably at cell-matrix boundaries.

Extracellular: 58-852
Helical: 853-873
Cytoplasmic: 874-1060