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NCAM1

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants.
Full Name
Neural Cell Adhesion Molecule 1
Alternative Names
Neural Cell Adhesion Molecule 1; NCAM; Antigen Recognized By Monoclonal Antibody 5.1H11; Neural Cell Adhesion Molecule, NCAM; CD56 Antigen; N-CAM-1; NCAM-1; MSK39; CD56;
Function
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

(Microbial infection) Acts as a receptor for rabies virus.

(Microbial infection) Acts as a receptor for Zika virus.
Biological Process
Cell adhesion Source: ProtInc
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL
Cellular Location
Isoform 1&2&3&4: Cell membrane
Isoform 5&6: Secreted
Topology
Extracellular: 20-718
Helical: 719-739
Cytoplasmic: 740-858

Anti-NCAM1 antibodies

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Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AG141
Application*: DB, E, IH, In Vivo, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CF304
Application*: ELISA, WB, IHC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1307
Application*: IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: A1306
Application*: ICC, IHC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1305
Application*: IF, IHC, IP
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: A1304
Application*: ICC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: A1303
Application*: FC, ICC, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1302
Application*: ELISA, FC, IF, IHC, IP, RIA, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: A1301
Application*: ELISA, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Zebrafish
Clone: A1300
Application*: ICC, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1299
Application*: ELISA, FC, ICC, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB321
Application*: IF, FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB320
Application*: IF, FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB319
Application*: IF, FC
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM315
Application*: IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb209
Application*: FC, IHC-F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb208
Application*: IHC-F, IF, IHC-P
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: MRQ-42
Application*: ELISA
Target: NCAM1
Host: Mouse
Specificity: Human
Clone: IHC056
Application*: P, E, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2G5-D6
Application*: F
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: H28-123
Application*: IP, FN, C, IC/IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: NCAM1/784
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: TULY56
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: NCAM16
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0137
Application*: F, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0136
Application*: C, IF, P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F303
Application*: IF, IH, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L223
Application*: E, FC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10B1836
Application*: FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.BB.490
Application*: FC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5K269
Application*: FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1567
Application*: E, IH, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: IML-43
Application*: IC, WB
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-4238
Application*: IF, IP, WB, F
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-4237
Application*: IP, FN, C, IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4236
Application*: F, IF, P, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4232
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2345
Application*: F, IF
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2344
Application*: F, P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2343
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2342
Application*: F, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2341
Application*: F, E
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Zebrafish
Clone: CBXC-1415
Application*: E, F, IF, IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1805
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: NCAM1/1496
Application*: P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM489
Application*: IF, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: NCAM1/795
Application*: F, IF, WB, P
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-1686
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: MEM-188
Application*: F
Target: NCAM1
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0737
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1511
Application*: E, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Pig
Clone: CBYY-C1510
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBYY-C1508
Application*: F, IC, IF, P, WB
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYY-C1507
Application*: F, IC, IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1505
Application*: IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1504
Application*: E, WB
Target: NCAM1
Host: Mouse
Specificity: Human
Clone: CBYY-C1503
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0632
Application*: E, F, IH, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0484
Application*: IC, IF, P, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0458
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0399
Application*: F, IF
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0133
Application*: F, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0057
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBYY-C0016
Application*: E, WB
Target: NCAM1
Host: Rat
Antibody Isotype: IgM
Specificity: Mouse, Human, Rat
Clone: CBFYC-2996
Application*: WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBFYC-2995
Application*: IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0246
Application*: E, WB, P, C, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0166
Application*: E, F, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYM-3026
Application*: F, IC, C, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H185
Application*: E, F, C, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5tukon56
Application*: P, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F47
Application*: F, IF
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 3H15L12
Application*: F, IC, IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G85
Application*: IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 3F97
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: 2Q692
Application*: E, C, WB
Target: NCAM1
Host: Rat
Antibody Isotype: IgM
Specificity: Mouse, Human, Rat
Clone: 12F8
Application*: WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Human
Clone: 10K139
Application*: C, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3H1571
Application*: F, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 39D5
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 123C3.D5
Application*: E, F, IF, IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B1827
Application*: E, F, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-1198
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-1197
Application*: P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1196
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1195
Application*: P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: T199
Application*: F, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBWJN-0726
Application*: IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MY31
Application*: F
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0694
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MOC-1
Application*: F, IC, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBWJN-0682
Application*: WB, E, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: LT56
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBWJN-0613
Application*: IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCD56
Application*: IH, F
Target: NCAM1
Host: Rat
Specificity: Mouse
Clone: CBWJN-0607
Application*: WB, IP, IF
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-0830
Application*: WB, IH, IC, F, IP
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B488
Application*: IH, F, E, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B332
Application*: P
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: A24-I
Application*: WB, IP, E, P, C
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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