LPO

This gene encodes a member of the peroxidase family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Following its secretion from salivary, mammary, and other mucosal glands, this enzyme catalyzes the generation of the antimicrobial substance hypothiocyanous acid. This gene is present in a gene cluster on chromosome 17. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

LPO

Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (By similarity).
May contribute to airway host defense against infection.

Defense response to bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Detection of chemical stimulus involved in sensory perception of bitter tasteManual Assertion Based On ExperimentIDA:UniProtKB
Hydrogen peroxide catabolic processIEA:UniProtKB-KW
Response to oxidative stress1 PublicationNAS:UniProtKB

Secreted