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IL17RB

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Full Name
Interleukin 17 Receptor B
Function
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Biological Process
Defense response Source: ProtInc
Regulation of cell growth Source: UniProtKB
Cellular Location
Isoform 1: Cell membrane
Isoform 2: Secreted
Topology
Extracellular: 18-292
Helical: 293-313
Cytoplasmic: 314-502

Anti-IL17RB antibodies

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Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I1560
Application*: F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I1320
Application*: E, WB
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-I1094
Application*: F, WB
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 9J28
Application*: WB
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I0822
Application*: F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 97C691
Application*: WB, IH
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0816
Application*: WB, F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0815
Application*: F, MC
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0814
Application*: IH, P, IC
Target: IL17RB
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 752101
Application*: F, MC
Target: IL17RB
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBYY-I0703
Application*: F
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I0365
Application*: F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0339
Application*: WB
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0152
Application*: WB, ED, MC, F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0151
Application*: WB, E
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 152316
Application*: WB
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 152309
Application*: WB, E
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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