Sign in or Register

IFNB1

This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Full Name
Interferon Beta 1
Alternative Names
Interferon Beta 1
Function
Has antiviral, antibacterial and anticancer activities.
Biological Process
Adaptive immune response Source: GO_Central
B cell activation involved in immune response Source: UniProtKB
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cell surface receptor signaling pathway Source: ProtInc
Cellular response to exogenous dsRNA Source: BHF-UCL
Cellular response to interferon-beta Source: BHF-UCL
Cellular response to virus Source: ARUK-UCL
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to virus Source: BHF-UCL
Humoral immune response Source: GO_Central
Natural killer cell activation Source: UniProtKB
Natural killer cell activation involved in immune response Source: GO_Central
Negative regulation of T cell differentiation Source: UniProtKB
Negative regulation of T-helper 2 cell cytokine production Source: UniProtKB
Negative regulation of viral genome replication Source: BHF-UCL
Positive regulation of apoptotic signaling pathway Source: UniProtKB
Positive regulation of innate immune response Source: UniProtKB
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: BHF-UCL
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Regulation of MHC class I biosynthetic process Source: UniProtKB
Response to exogenous dsRNA Source: MGI
Response to virus Source: UniProtKB
T cell activation involved in immune response Source: GO_Central
Type I interferon signaling pathway Source: BHF-UCL
Cellular Location
Secreted
View more

Anti-IFNB1 antibodies

+ Filters
Loading...

Mouse Anti-IFNB1 Recombinant Antibody (B-A15) (CBMAB-I1954-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-A15
Application*: F
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (AG92) (V2LY-0524-LY64)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: AG92
Application*: B, N, WB
Functional Assay
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A396) (CBMAB-AP3923LY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG
Specificity: Pig
Clone: A396
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A395) (CBMAB-AP3906LY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG
Specificity: Chicken
Clone: A395
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A394) (CBMAB-AP3905LY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG
Specificity: Chicken
Clone: A394
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A393) (CBMAB-AP3904LY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG
Specificity: Chicken
Clone: A393
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A392) (CBMAB-AP3903LY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG
Specificity: Cattle
Clone: A392
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A391) (CBMAB-AP3907LY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: A391
Application*: ICC, IHC, IP, WB
Datasheet SDS

Rabbit Anti-IFNB1 Recombinant Antibody (D1D7G) (CBMAB-CP1102-LY)

Go to compareCompare
Target: IFNB1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D1D7G
Application*: WB
Datasheet SDS

Rabbit Anti-IFNB1 Recombinant Antibody (D2J1D) (CBMAB-CP1101-LY)

Go to compareCompare
Target: IFNB1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: D2J1D
Application*: WB, F
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (CBYY-I1525) (CBMAB-I2695-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1525
Application*: E, N
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (CBYY-I1304) (CBMAB-I2473-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I1304
Application*: E, IH, IP, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (CBYY-I0898) (CBMAB-I2066-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0898
Application*: E
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (BG6) (CBMAB-I2014-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: BG6
Application*: E, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (BF3) (CBMAB-I2002-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BF3
Application*: E, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (BD9) (CBMAB-I1986-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: BD9
Application*: E, WB
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (BB4) (CBMAB-I1969-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: BB4
Application*: WB, SE
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (B894M) (CBMAB-I1952-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: B894M
Application*: E, WB, P, IP
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (A1) (CBMAB-I1850-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1
Application*: WB, IC, P, C, E, IP, IF, F, FN
Datasheet SDS

Rat Anti-IFNB1 Recombinant Antibody (7F-D3) (CBMAB-I1673-YY)

Go to compareCompare
Target: IFNB1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 7F-D3
Application*: WB, E, N, F
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (CBYY-I0733) (CBMAB-I1635-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0733
Application*: N
Datasheet SDS

Mouse Anti-IFNB1 Recombinant Antibody (CBYY-I0732) (CBMAB-I1634-YY)

Go to compareCompare
Target: IFNB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0732
Application*: WB, N
Datasheet SDS

Rat Anti-IFNB1 Recombinant Antibody (CBYY-I0451) (CBMAB-I1051-YY)

Go to compareCompare
Target: IFNB1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-I0451
Application*: E, F, IH, IP, N
Datasheet SDS

Hamster Anti-IFNB1 Recombinant Antibody (CBYY-I0333) (CBMAB-I0870-YY)

Go to compareCompare
Target: IFNB1
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYY-I0333
Application*: IP, N, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry