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ICAM2

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

Intercellular Adhesion Molecule 2

Function

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

Biological Process

Cell adhesion Source: GO_Central
Cell-cell adhesion Source: InterPro

Cellular Location

Membrane; Microvillus. Co-localizes with RDX, EZR and MSN in microvilli.

Topology

Extracellular: 25-223
Helical: 224-248
Cytoplasmic: 249-275

Anti-ICAM2 antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-ICAM2 Recombinant Antibody (CBYY-C0546) (CBMAB-C1638-YY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-C0546

Application*: E, F, IH

Rat Anti-ICAM2 Recombinant Antibody (5K55) (CBMAB-C7813-LY)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: 5K55

Application*: F, IH, IP

Rat Anti-ICAM2 Recombinant Antibody (3C4) (CBMAB-C1090-LY)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 3C4

Application*: C, FN, P, F

Rat Anti-ICAM2 Recombinant Antibody (10B512) (CBMAB-C0166-LY)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 10B512

Application*: F, IP

Rabbit Anti-ICAM2 Recombinant Antibody (EG1600) (CBMAB-EN1914-LY)

SDS

Target: ICAM2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1600

Application*: WB: 1:500~1:1000 ELISA: 1:10000

Rabbit Anti-ICAM2 Recombinant Antibody (D7P2Q) (CBMAB-CP1086-LY)

SDS

Target: ICAM2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: D7P2Q

Application*: WB, IP, P, IF (IC), F

Mouse Anti-ICAM2 Recombinant Antibody (CBR-IC2/2) (CBMAB-C3580-CN)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBR-IC2/2

Application*: FC, IH, IP

Mouse Anti-ICAM2 Recombinant Antibody (3H1795) (CBMAB-C3578-CN)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3H1795

Application*: FC, IP, WB

Mouse Anti-ICAM2 Recombinant Antibody (B-R7) (CBMAB-C5048WJ)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: B-R7

Application*: E

Mouse Anti-ICAM2 Recombinant Antibody (CBRIC2/2) (CBMAB-C2949WJ)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBRIC2/2

Application*: C, FN, IP, F

Mouse Anti-ICAM2 Recombinant Antibody (B-T1) (CBMAB-C2948WJ)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: B-T1

Application*: E, IP, F, FN

Rat Anti-ICAM2 Recombinant Antibody (CBXC-1648) (CBMAB-C2932-CQ)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBXC-1648

Application*: F, IH, IP

Rat Anti-ICAM2 Recombinant Antibody (3C4 (MIC2/4)) (CBMAB-C2828-CQ)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG

Specificity: Mouse

Clone: 3C4 (MIC2/4)

Application*: F, IH, IP

Human Anti-ICAM2 Recombinant Antibody (CBXC-0935) (CBMAB-C2051-CQ)

SDS

Target: ICAM2

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-0935

Application*: F

Mouse Anti-ICAM2 Recombinant Antibody (CBYY-C2542) (CBMAB-C3983-YY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C2542

Application*: F

Mouse Anti-ICAM2 Recombinant Antibody (CBYY-C0525) (CBMAB-C1565-YY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-C0525

Application*: F, IH, IP

Rat Anti-ICAM2 Recombinant Antibody (CBYY-C0467) (CBMAB-C1425-YY)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBYY-C0467

Application*: F, IH, IP

Rabbit Anti-ICAM2 Recombinant Antibody (CBFYC-2746) (CBMAB-C2821-FY)

SDS

Target: ICAM2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBFYC-2746

Application*: F

Rat Anti-ICAM2 Recombinant Antibody (CBFYC-0186) (CBMAB-C0209-FY)

SDS

Target: ICAM2

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYC-0186

Application*: F, IP

Rabbit Anti-ICAM2 Recombinant Antibody (CBYY-I1688) (CBMAB-I2858-YY)

SDS

Target: ICAM2

Host: Rabbit

Specificity: Human

Clone: CBYY-I1688

Application*: WB, IP, P, IF, F

Mouse Anti-ICAM2 Recombinant Antibody (CBYY-I1097) (CBMAB-I2265-YY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I1097

Application*: P

Mouse Anti-ICAM2 Recombinant Antibody (CBYY-I0784) (CBMAB-I1733-YY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I0784

Application*: WB

Mouse Anti-ICAM2 Recombinant Antibody (CBYY-I0517) (CBMAB-I1182-YY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I0517

Application*: WB, F, IF, IP

Mouse Anti-ICAM2 Recombinant Antibody (6D42) (CBMAB-C8211-LY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 6D42

Application*: E, F, IH

Mouse Anti-ICAM2 Recombinant Antibody (6A356) (CBMAB-C8016-LY)

SDS

Target: ICAM2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 6A356

Application*: F, IH, IP

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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