HMMR

The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Full Name

hyaluronan mediated motility receptor

Function

Receptor for hyaluronic acid (HA) (By similarity).

Involved in cell motility (By similarity).

When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).

Biological Process

Cytoplasm; Spindle; Cell surface

Anti-HMMR antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-HMMR Recombinant Antibody (2D6) (CBMAB-C4914-LY)

Datasheet

SDS

Target: HMMR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2D6

Application*: P, C, F, IC/IF

Mouse Anti-HMMR Recombinant Antibody (2F2C9) (CBMAB-R0267-CN)

Datasheet

SDS

Target: HMMR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2F2C9

Application*: WB, F, E, MC

Rabbit Anti-HMMR Recombinant Antibody (EG1526) (CBMAB-EN1825-LY)

Datasheet

SDS

Target: HMMR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1526

Application*: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)