FTMT

FTMT (Ferritin Mitochondrial) is a Protein Coding gene. Diseases associated with FTMT include Friedreich Ataxia 1 and Restless Legs Syndrome. Among its related pathways are Ferroptosis. Gene Ontology (GO) annotations related to this gene include ferric iron binding and ferroxidase activity. An important paralog of this gene is FTH1.

Full Name

ferritin mitochondrial

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Biological Process

Cellular iron ion homeostasis Source: BHF-UCL
Intracellular sequestering of iron ion Source: GO_Central
Iron ion transport Source: InterPro
Positive regulation of aconitate hydratase activity Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of lyase activity Source: BHF-UCL
Positive regulation of succinate dehydrogenase activity Source: BHF-UCL

Cellular Location

Mitochondrion

Anti-FTMT antibodies

Mouse Anti-FTMT Recombinant Antibody (6G3) (CBMAB-A3217-LY)

Datasheet

SDS

Target: FTMT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 6G3

Application*: WB, E

Mouse Anti-FTMT (AA 143-242) Recombinant Antibody (CBXF-3227) (CBMAB-F3922-CQ)

Datasheet

SDS

Target: FTMT

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-3227

Application*: E, WB

Mouse Anti-FTMT Recombinant Antibody (CBXF-0951) (CBMAB-F3218-CQ)

Datasheet

SDS

Target: FTMT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXF-0951

Application*: SE, WB, E, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)