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ELOB

ELOB is the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. ELOB activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A plays a role as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for ELOB.
Full Name
Elongin B
Biological Process
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: FlyBase
Protein-containing complex assembly Source: ProtInc
Protein ubiquitination Source: UniProtKB-UniPathway
Transcription elongation from RNA polymerase II promoter Source: ProtInc
Cellular Location
Nucleus
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Anti-ELOB antibodies

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Mouse Anti-ELOB Recombinant Antibody (2B4) (CBMAB-A8939-LY)

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Target: ELOB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 2B4
Application*: WB, E, IF
Datasheet SDS

Mouse Anti-ELOB Recombinant Antibody (CBYJT-1218) (CBMAB-T0233-YJ)

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Target: ELOB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: CBYJT-1218
Application*: WB, E, IF
Datasheet SDS

Mouse Anti-ELOB Recombinant Antibody (CBYJT-1217) (CBMAB-T0232-YJ)

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Target: ELOB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYJT-1217
Application*: WB, IP, IF, E, P
Datasheet SDS

Rabbit Anti-ELOB Recombinant Antibody (CBFYE-0799) (CBMAB-E1247-FY)

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Target: ELOB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYE-0799
Application*: WB, P
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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