CTSF

CTSE (Cathepsin E) is a Protein Coding gene. Diseases associated with CTSE include Gastric Adenocarcinoma and Rosai-Dorfman Disease. Among its related pathways are Innate Immune System and MHC class II antigen presentation. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and aspartic-type endopeptidase activity. An important paralog of this gene is PGA3.

Cathepsin E

Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.

Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Proteolysis Source: ProtInc
Proteolysis involved in cellular protein catabolic process Source: GO_Central

Lysosome

Ceroid lipofuscinosis, neuronal, 13 (CLN13):
A form of neuronal ceroid lipofuscinosis characterized by adult onset of progressive cognitive decline and motor dysfunction leading to dementia and often early death. Some patients develop seizures. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material.