CSF3

CSF3 (Colony Stimulating Factor 3) is a Protein Coding gene. Diseases associated with CSF3 include Neutropenia and Severe Congenital Neutropenia. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include enzyme binding and growth factor activity.

Colony Stimulating Factor 3

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

Cellular response to cytokine stimulus Source: BHF-UCL
Cellular response to lipopolysaccharide Source: Ensembl
Cytokine-mediated signaling pathway Source: Reactome
Granulocyte differentiation Source: UniProtKB
Immune response Source: InterPro
Multicellular organism development Source: ProtInc
Negative regulation of neuron death Source: Ensembl
Positive regulation of actin cytoskeleton reorganization Source: BHF-UCL
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of DNA-binding transcription factor activity Source: BHF-UCL
Positive regulation of myeloid cell differentiation Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation Source: BHF-UCL
Positive regulation of peptidyl-tyrosine phosphorylation Source: BHF-UCL
Positive regulation of phosphatidylinositol 3-kinase signaling Source: BHF-UCL
Positive regulation of protein binding Source: BHF-UCL
Positive regulation of protein kinase B signaling Source: BHF-UCL
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Response to ethanol Source: Ensembl

Secreted

O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).