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Mouse Anti-CSF3 Recombinant Antibody (CBFYH-0108) (V2LY-1206-LY1470)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0108
Antibody Isotype
IgG1
Application
ELISA, WB, Neutralization

Basic Information

Immunogen
E. coli-derived recombinant human G-CSF (Ala30-Pro204).
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:1,000
ELISA0.2-0.4 µg/ml
Neutralization0.02-0.04 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Colony Stimulating Factor 3
Entrez Gene ID
1440
UniProt ID
P09919
Function
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Biological Process
Cellular response to cytokine stimulus Source: BHF-UCL
Cellular response to lipopolysaccharide Source: Ensembl
Cytokine-mediated signaling pathway Source: Reactome
Granulocyte differentiation Source: UniProtKB
Immune response Source: InterPro
Multicellular organism development Source: ProtInc
Negative regulation of neuron death Source: Ensembl
Positive regulation of actin cytoskeleton reorganization Source: BHF-UCL
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of DNA-binding transcription factor activity Source: BHF-UCL
Positive regulation of myeloid cell differentiation Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation Source: BHF-UCL
Positive regulation of peptidyl-tyrosine phosphorylation Source: BHF-UCL
Positive regulation of phosphatidylinositol 3-kinase signaling Source: BHF-UCL
Positive regulation of protein binding Source: BHF-UCL
Positive regulation of protein kinase B signaling Source: BHF-UCL
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Response to ethanol Source: Ensembl
Cellular Location
Secreted
PTM
O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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