CALB2

This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Calbindin 2

Calretinin is a calcium-binding protein which is abundant in auditory neurons.

Regulation of cytosolic calcium ion concentration Source: GO_Central
Regulation of long-term synaptic potentiation Source: GO_Central
Regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central

Cuticular plate; Cytosol; Nucleus; Synaptic membrane; Dendrite; Gap junction; Neuron projection; Parallel fiber to Purkinje cell synapse; Stereocilium; Synapse; Terminal bouton