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ACP5

ACP5 encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.
Full Name
Acid Phosphatase 5, Tartrate Resistant
Function
Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Biological Process
Bone resorption
Ossification
Riboflavin metabolic process
Cellular Location
Lysosome
Involvement in disease
Spondyloenchondrodysplasia with immune dysregulation (SPENCDI): A disease characterized by vertebral and metaphyseal dysplasia, spasticity with cerebral calcifications, and strong predisposition to autoimmune diseases. The skeletal dysplasia is characterized by radiolucent and irregular spondylar and metaphyseal lesions that represent islands of chondroid tissue within bone.

Anti-ACP5 antibodies

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Target: ACP5
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: V2-347940
Application*: F, P, IF, MC
Target: ACP5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-347939
Application*: WB, IC, P, C, E
Target: ACP5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-347936
Application*: WB
Target: ACP5
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: V2-179379
Application*: WB, IH, IP
Target: ACP5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-179378
Application*: E, WB, P, IF, IC, F
Target: ACP5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-179377
Application*: E, F, P, WB
Target: ACP5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179376
Application*: E, IF, WB
Target: ACP5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-179373
Application*: E, IH, WB
Target: ACP5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-179372
Application*: E, F, WB
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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