AADAT

AADAT is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the ma

Aminoadipate Aminotransferase

Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).

2-oxoglutarate metabolic process
Alpha-amino acid metabolic process
Biosynthetic process
Glutamate metabolic process
Kynurenine metabolic process
L-lysine catabolic process to acetyl-CoA via saccharopine
Lysine catabolic process
Tryptophan catabolic process

Mitochondrion