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SORD Matched Antibody Pair (1122) (APMAB-1122LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-SORD monoclonal antibody, 100 ug
Detection Antibody
Anti-SORD Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
Alternative Names
Sorbitol Dehydrogenase; L-Iditol 2-Dehydrogenase; EC 1.1.1.14; Epididymis Secretory Sperm Binding Protein Li 95n; HEL-S-95n; EC 1.1.1; SORD1;
Entrez Gene ID
6652
UniProt ID
Q00796
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For research use only. Not intended for any clinical use.

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