ING1 Matched Antibody Pair (641) (APMAB-641LY)

See all ING1 antibodies

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-ING1 polyclonal antibody, 100 ug

Detection Antibody

Anti-ING1 Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Alternative Names

Inhibitor Of Growth Family Member 1

Entrez Gene ID

3621

UniProt ID

Q9UK53

More Infomation

References

Yang, Y., Ma, B., Djamshidi, M., Zhang, Q., Sarkar, A., Chanda, A., ... & Riabowol, K. (2023). ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat. European Journal of Cell Biology, 102(3), 151341.

Bartsch, S., Mirzakhani, K., Neubert, L., Stenzel, A., Ehsani, M., Esmaeili, M., ... & Baniahmad, A. (2021). Antithetic hTERT regulation by androgens in prostate cancer cells: hTERT inhibition is mediated by the ING1 and ING2 tumor suppressors. Cancers, 13(16), 4025.

Smolle, E., Fink-Neuboeck, N., Lindenmann, J., Smolle-Juettner, F., & Pichler, M. (2019). The biological and clinical relevance of inhibitor of growth (ING) genes in non-Small cell lung cancer. Cancers, 11(8), 1118.

Leighton, L. J., Zhao, Q., Li, X., Dai, C., Marshall, P. R., Liu, S., ... & Wei, W. (2018). A functional role for the epigenetic regulator ING1 in activity-induced gene expression in primary cortical neurons. Neuroscience, 369, 248-260.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

ING1 Matched Antibody Pair (642)

Antibody Pairs

ING1 Matched Antibody Pair (642)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Second antibody and isotype control

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