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HOXB7 Matched Antibody Pair (566) (APMAB-566LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-HOXB7 monoclonal, IgG1 antibody, 100 ug
Detection Antibody
Anti-HOXB7 Biotinylated mouse monoclonal, IgG1 antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
Alternative Names
Homeobox B7; Homeobox Protein HHO.C1; Homeobox Protein Hox-2C; Homeo Box B7; HOX2C; Homeobox Protein Hox-B7;
Entrez Gene ID
3217
UniProt ID
P09629
More Infomation

Komatsuda, H., Wakisaka, R., Kono, M., Kumai, T., Hayashi, R., Yamaki, H., ... & Kobayashi, H. (2023). Mitogen‐activated protein kinase inhibition augments the T cell response against HOXB7‐expressing tumor through human leukocyte antigen upregulation. Cancer Science, 114(2), 399.

de Bessa Garcia, S. A., Araújo, M., Pereira, T., & Freitas, R. (2021). HOXB7 overexpression leads triple-negative breast Cancer cells to a less aggressive phenotype. Biomedicines, 9(5), 515.

Casari, G., Resca, E., Giorgini, A., Candini, O., Petrachi, T., Piccinno, M. S., ... & Veronesi, E. (2021). Microfragmented adipose tissue is associated with improved ex vivo performance linked to HOXB7 and b-FGF expression. Stem Cell Research & Therapy, 12(1), 1-13.

Zhou, T., Fu, H., Dong, B., Dai, L., Yang, Y., Yan, W., & Shen, L. (2020). HOXB7 mediates cisplatin resistance in esophageal squamous cell carcinoma through involvement of DNA damage repair. Thoracic Cancer, 11(11), 3071-3085.

Cheng, W., Shi, X., Lin, M., Yao, Q., Ma, J., & Li, J. (2020). LncRNA MAGI2-AS3 overexpression sensitizes esophageal cancer cells to irradiation through down-regulation of HOXB7 via EZH2. Frontiers in Cell and Developmental Biology, 8, 552822.

Zhang, D. W., Wu, H. Y., Zhu, C. R., & Wu, D. D. (2020). CircRNA hsa_circ_0070934 functions as a competitive endogenous RNA to regulate HOXB7 expression by sponging miR‑1236‑3p in cutaneous squamous cell carcinoma. International Journal of Oncology, 57(2), 478-487.

Dai, L., Hu, W., Yang, Z., Chen, D., He, B., Chen, Y., ... & Zheng, S. (2019). Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis. Laboratory Investigation, 99(6), 736-748.

Foppiani, E. M., Candini, O., Mastrolia, I., Murgia, A., Grisendi, G., Samarelli, A. V., ... & Dominici, M. (2019). Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors. Stem Cell Research & Therapy, 10(1), 1-12.

Monterisi, S., Lo Riso, P., Russo, K., Bertalot, G., Vecchi, M., Testa, G., ... & Bianchi, F. (2018). HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype. Oncogene, 37(26), 3575-3588.

Gao, D., & Chen, H. Q. (2018). Specific knockdown of HOXB7 inhibits cutaneous squamous cell carcinoma cell migration and invasion while inducing apoptosis via the Wnt/β-catenin signaling pathway. American Journal of Physiology-Cell Physiology, 315(5), C675-C686.

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For research use only. Not intended for any clinical use.

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