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GSTP1 Matched Antibody Pair (511) (APMAB-511LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-GSTP1 polyclonal antibody, 100 ug
Detection Antibody
Anti-GSTP1 Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]
Alternative Names
Glutathione S-Transferase Pi 1; GST Class-Pi; EC 2.5.1.18; GSTP1-1; FAEES3; GST3; Fatty Acid Ethyl Ester Synthase III; Epididymis Secretory Protein Li 22;
Entrez Gene ID
2950
UniProt ID
P09211
More Infomation

Lei, X., Du, L., Yu, W., Wang, Y., Ma, N., & Qu, B. (2021). GSTP1 as a novel target in radiation induced lung injury. Journal of Translational Medicine, 19, 1-5.

Feng, Q., Li, X., Sun, W., Sun, M., Li, Z., Sheng, H., ... & Shan, C. (2020). Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1. Biochemical Pharmacology, 178, 114092.

Cui, J., Li, G., Yin, J., Li, L., Tan, Y., Wei, H., ... & Yi, L. (2020). GSTP1 and cancer: Expression, methylation, polymorphisms and signaling. International Journal of Oncology, 56(4), 867-878.

Santric, V., Djokic, M., Suvakov, S., Pljesa-Ercegovac, M., Nikitovic, M., Radic, T., ... & Savic-Radojevic, A. (2020). GSTP1 rs1138272 polymorphism affects prostate cancer risk. Medicina, 56(3), 128.

Lei, K., Gu, X., Alvarado, A. G., Du, Y., Luo, S., Ahn, E. H., ... & Ye, K. (2020). Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma. Journal of hematology & oncology, 13, 1-21.

Farmohammadi, A., Arab-Yarmohammadi, V., & Ramzanpour, R. (2020). Association analysis of rs1695 and rs1138272 variations in GSTP1 gene and breast cancer susceptibility. Asian Pacific Journal of Cancer Prevention: APJCP, 21(4), 1167.

Du, Y., Zhang, H., Xu, Y., Ding, Y., Chen, X., Mei, Z., ... & Jie, Z. (2019). Association among genetic polymorphisms of GSTP1, HO-1, and SOD-3 and chronic obstructive pulmonary disease susceptibility. International Journal of Chronic Obstructive Pulmonary Disease, 2081-2088.

Gurioli, G., Martignano, F., Salvi, S., Costantini, M., Gunelli, R., & Casadio, V. (2018). GSTP1 methylation in cancer: a liquid biopsy biomarker?. Clinical Chemistry and Laboratory Medicine (CCLM), 56(5), 702-717.

Checa-Rojas, A., Delgadillo-Silva, L. F., del Castillo Velasco-Herrera, M., Andrade-Domínguez, A., Gil, J., Santillán, O., ... & Encarnación-Guevara, S. (2018). GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer. Oncotarget, 9(31), 21696.

Lin, C., Xie, L., Lu, Y., Hu, Z., & Chang, J. (2018). miR-133b reverses cisplatin resistance by targeting GSTP1 in cisplatin-resistant lung cancer cells. International Journal of Molecular Medicine, 41(4), 2050-2058.

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For research use only. Not intended for any clinical use.

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