GSDMD Matched Antibody Pair (505) (APMAB-505LY)

Xie, W. J., Xia, S., Warshel, A., & Wu, H. (2022). Electrostatic influence on IL-1 transport through the GSDMD pore. Proceedings of the National Academy of Sciences, 119(6), e2120287119.

Liu, Y., Xue, N., Zhang, B., Lv, H., & Li, S. (2022). Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway. Biomolecules, 12(7), 927.

Jiang, S., Zhang, H., Li, X., Yi, B., Huang, L., Hu, Z., ... & Zhang, W. (2021). Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway. The Journal of Steroid Biochemistry and Molecular Biology, 206, 105789.

Zhang, J., Dai, Y., Yang, Y., & Xu, J. (2021). Calcitriol alleviates hyperosmotic stress-induced corneal epithelial cell damage via inhibiting the NLRP3–ASC–caspase-1–GSDMD pyroptosis pathway in dry eye disease. Journal of Inflammation Research, 14, 2955.

Yan, H., Luo, B., Wu, X., Guan, F., Yu, X., Zhao, L., ... & Yuan, J. (2021). Cisplatin induces pyroptosis via activation of MEG3/NLRP3/caspase-1/GSDMD pathway in triple-negative breast cancer. International Journal of Biological Sciences, 17(10), 2606.

Li, W., Deng, M., Loughran, P. A., Yang, M., Lin, M., Yang, C., ... & Scott, M. J. (2020). LPS induces active HMGB1 release from hepatocytes into exosomes through the coordinated activities of TLR4 and caspase-11/GSDMD signaling. Frontiers in Immunology, 11, 229.

Yang, Y., Liu, P. Y., Bao, W., Chen, S. J., Wu, F. S., & Zhu, P. Y. (2020). Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. BMC cancer, 20, 1-19.

Schwarzer, R., Jiao, H., Wachsmuth, L., Tresch, A., & Pasparakis, M. (2020). FADD and caspase-8 regulate gut homeostasis and inflammation by controlling MLKL-and GSDMD-mediated death of intestinal epithelial cells. Immunity, 52(6), 978-993.

Karmakar, M., Minns, M., Greenberg, E. N., Diaz-Aponte, J., Pestonjamasp, K., Johnson, J. L., ... & Pearlman, E. (2020). N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Nature communications, 11(1), 2212.

Pandeya, A., Li, L., Li, Z., & Wei, Y. (2019). Gasdermin D (GSDMD) as a new target for the treatment of infection. Medchemcomm, 10(5), 660-667.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

GSDMD Matched Antibody Pair (504)

Antibody Pairs

GSDMD Matched Antibody Pair (504)

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GSDMD Matched Antibody Pair (504)

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Isotype control