CD40 Matched Antibody Pair (222) (APMAB-222LY)

Tang, T., Cheng, X., Truong, B., Sun, L., Yang, X., & Wang, H. (2021). Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint. Pharmacology & Therapeutics, 219, 107709.

Bullock, T. N. (2021). CD40 stimulation as a molecular adjuvant for cancer vaccines and other immunotherapies. Cellular & Molecular Immunology, 1-9.

Dakal, T. C., Dhabhai, B., Agarwal, D., Gupta, R., Nagda, G., Meena, A. R., ... & Sharma, A. (2020). Mechanistic basis of co-stimulatory CD40-CD40L ligation mediated regulation of immune responses in cancer and autoimmune disorders. Immunobiology, 225(2), 151899.

Richards, D. M., Sefrin, J. P., Gieffers, C., Hill, O., & Merz, C. (2020). Concepts for agonistic targeting of CD40 in immuno-oncology. Human vaccines & immunotherapeutics, 16(2), 377-387.

Lai, J. H., Luo, S. F., & Ho, L. J. (2019). Targeting the CD40-CD154 signaling pathway for treatment of autoimmune arthritis. Cells, 8(8), 927.

Schlievert, P. M., Cahill, M. P., Hostager, B. S., Brosnahan, A. J., Klingelhutz, A. J., Gourronc, F. A., ... & Leung, D. Y. (2019). Staphylococcal superantigens stimulate epithelial cells through CD40 to produce chemokines. MBio, 10(2), e00214-19.

Foster, A. E., Mahendravada, A., Shinners, N. P., Chang, W. C., Crisostomo, J., Lu, A., ... & Spencer, D. M. (2017). Regulated expansion and survival of chimeric antigen receptor-modified T cells using small molecule-dependent inducible MyD88/CD40. Molecular Therapy, 25(9), 2176-2188.

Chen, J., Song, Y., Bojadzic, D., Tamayo-Garcia, A., Landin, A. M., Blomberg, B. B., & Buchwald, P. (2017). Small-molecule inhibitors of the CD40–CD40L costimulatory protein–protein interaction. Journal of medicinal chemistry, 60(21), 8906-8922.

Aarts, S. A., Seijkens, T. T., Kusters, P. J., van der Pol, S. M., Zarzycka, B., Heijnen, P. D., ... & Lutgens, E. (2017). Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. Journal of neuroinflammation, 14(1), 1-14.

Chen, J., Li, J. H., Zhao, S. J., Wang, D. Y., Zhang, W. Z., & Liang, W. J. (2017). Clinical significance of costimulatory molecules CD40/CD40L and CD134/CD134L in coronary heart disease: a case-control study. Medicine, 96(32).

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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