BID Matched Antibody Pair (137) (APMAB-137LY)

Name: BID Matched Antibody Pair (137)
SKU: APMAB-137LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-BID polyclonal antibody, 100 ug

Detection Antibody

Anti-BID Mouse monoclonal, IgG2a antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

Alternative Names

BH3 Interacting Domain Death Agonist; P22 BID; BH3-Interacting Domain Death Agonist; Human BID Coding Sequence; Apoptic Death Agonist; BID Isoform ES(1b);

Entrez Gene ID

637

UniProt ID

P55957

More Infomation

References

Maxa, M., Schaeper, U., Dames, S., Vollmar, B., & Kuhla, A. (2019). Liver-specific bid silencing inhibits apap-induced cell death in mice. Apoptosis, 24(11), 934-945.

Wicki, S., Gurzeler, U., Corazza, N., Genitsch, V., Wong, W. W. L., & Kaufmann, T. (2018). Loss of BID delays FASL-induced cell death of mouse neutrophils and aggravates DSS-induced weight loss. International journal of molecular sciences, 19(3), 684.

Tsuno, T., Kanno, S., Ryoichi, I., Tanigawa, N., & Ueba, T. (2018). Abstract B13: New drug repositioning of low-dose pegylated IFN-alpha in combination with BH3 interacting domain death agonist gene and radiation therapy as a cancer treatment regimen.

Zhang, F., Qiu, Q., Song, X., Chen, Y., Wu, J., & Liang, M. (2017). Signal‐Regulated Protein Kinases/Protein Kinase B‐p53‐BH3–Interacting Domain Death Agonist Pathway Regulates Gingipain‐Induced Apoptosis in Osteoblasts. Journal of periodontology, 88(11), e200-e210.

Hu, W. L., Dong, H. Y., Li, Y., Ojcius, D. M., Li, S. J., & Yan, J. (2017). Bid-induced release of AIF/EndoG from mitochondria causes apoptosis of macrophages during infection with Leptospira interrogans. Frontiers in cellular and infection microbiology, 7, 471.

Gao, X., Liu, Y., Xie, Y., Wang, Y., & Qi, S. (2017). Remote ischemic postconditioning confers neuroprotective effects via inhibition of the BID-mediated mitochondrial apoptotic pathway. Molecular medicine reports, 16(1), 515-522.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

BID Matched Antibody Pair (136)

Antibody Pairs

BID Matched Antibody Pair (136)

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BID Matched Antibody Pair (136)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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Second antibody and isotype control

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