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Mouse Anti-ZXDC Recombinant Antibody (3C12) (CBMAB-0687-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3C12
Antibody Isotype
IgG1
Application
IP, MA, WB

Basic Information

Immunogen
Full length
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ZXDC
Introduction
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Entrez Gene ID
79364
UniProt ID
Q2QGD7
Alternative Names
FLJ13861; MGC11349
Function
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Biological Process
Biological Process positive regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Sumoylated at Lys-660 with SUMO1, SUMO2 and SUMO3; sumoylation enhances the activity of the transcriptional activation domain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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