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Mouse Anti-ZNF81 Recombinant Antibody (3G3) (CBMAB-Z0670-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3G3
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
ZNF81 (AA1-122) partial recombinant protein with GST tag. Immunogen sequence: MPANEDAPQP GEHGSACEVS VSFEDVTVDF SREEWQQLDS TQRRLYQDVM LENYSHLLSV GFEVPKPEVI FKLEQGEGPW TLEGEAPHQS CSDGKFGIKP SQRRISGKST FHSEMEGEDT LC
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid

Target

Full Name
zinc finger protein 81
Introduction
This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability.
Entrez Gene ID
347344
UniProt ID
P51508
Alternative Names
HFZ20; MRX45
Function
May be involved in transcriptional regulation.
Biological Process
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving ZNF81 is found in a severe intellectual disability patient. Translocation t(X;9)(p11.23;q34.3).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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