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Mouse Anti-ZNF639 Recombinant Antibody (2B2) (CBMAB-0764-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2B2
Antibody Isotype
IgG2a
Application
ChIP, IP, MA, WB

Basic Information

Immunogen
Recombinant peptide (aa 406-485)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ZNF639
Introduction
This gene encodes a member of the Kruppel-like zinc finger family of proteins. Amplification and overexpression of this gene have been observed in esophageal squamous cell carcinoma. The encoded protein has been shown to bind DNA in a sequence-specific manner and may regulate HIV-1 gene expression. Alternative splicing results in multiple transcript variants. Binds DNA and may function as a transcriptional repressor.
Entrez Gene ID
51193
UniProt ID
Q9UID6
Alternative Names
ANC-2H01; ZASC1
Function
Binds DNA and may function as a transcriptional repressor.
Biological Process
Biological Process negative regulation by host of viral transcription Source:UniProtKB1 Publication
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process positive regulation by host of viral transcription Source:UniProtKB1 Publication
Biological Process positive regulation of cell growth Source:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:NTNU_SB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process viral entry into host cell Source:UniProtKB1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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